[D-Ala2]leucine-enkephalin
Based on 1 Customer Validation
[D-Ala2]leucine-enkephalin, a delta opioid agonist, is a degradation resistant long-acting Leu-enkephalin analog used to study the signaling pathway of delta opioid receptors.
For research use only. We do not sell to patients.
- Purity: 98.92%
- CAS No.: 64963-01-5
- Formula: C29H39N5O7
- Molecular Weight:569.65
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Storage:
Sealed storage, away from moisture.
Powder -80°C, 2 years , -20°C, 1 year* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
![[D-Ala2]leucine-enkephalin Chemical Structure](https://file.medchemexpress.com/product_pic/hy-p0098.gif "Click to View [D-Ala2]leucine-enkephalin Chemical Structure")
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
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Help & FAQs
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All Opioid Receptor Isoforms
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Biological Activity
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δ Opioid Receptor/DOR |
[D-Ala2]leucine-enkephalin is widely distributed in the human body and possesses extremely vital physiological functions. It exerts unique effects on brain cells, being capable of activating dormant brain cells and facilitating the recovery of sequelae caused by brain damage. It also plays an essential role in immune function, including enhancing the activity of the immune system, T lymphocytes, NK cells and macrophages, exerting antiviral effects, and promoting the secretion of gamma-interferon. Additionally, it participates in immune regulation by stimulating endocrine cell secretion through activated immune cells, thereby influencing the gene regulation and expression functions of DNA.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 64963-01-5
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Appearance Solid
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Molecular Weight 569.65
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Formula C29H39N5O7
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Color White to off-white
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Sequence
Tyr-{d-Ala}-Gly-Phe-Leu
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Sequence Shortening
Y-{d-Ala}-GFL
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Sealed storage, away from moisture
Powder -80°C 2 years -20°C 1 year * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Solvent & Solubility
H2O : 50 mg/mL (87.77 mM; Need ultrasonic)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
For the following dissolution methods, please prepare the working solution directly:
It is recommended to prepare fresh solutions and use them promptly within a short period of time.
The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.
Add each solvent one by one: PBS
Solubility: 50 mg/mL (87.77 mM); Clear solution; Need ultrasonic
Purity & Documentation
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Data Sheet (245 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| H2O | 1 mM | 1.7555 mL | 8.7773 mL | 17.5546 mL | 43.8866 mL |
| 5 mM | 0.3511 mL | 1.7555 mL | 3.5109 mL | 8.7773 mL | |
| 10 mM | 0.1755 mL | 0.8777 mL | 1.7555 mL | 4.3887 mL | |
| 15 mM | 0.1170 mL | 0.5852 mL | 1.1703 mL | 2.9258 mL | |
| 20 mM | 0.0878 mL | 0.4389 mL | 0.8777 mL | 2.1943 mL | |
| 25 mM | 0.0702 mL | 0.3511 mL | 0.7022 mL | 1.7555 mL | |
| 30 mM | 0.0585 mL | 0.2926 mL | 0.5852 mL | 1.4629 mL | |
| 40 mM | 0.0439 mL | 0.2194 mL | 0.4389 mL | 1.0972 mL | |
| 50 mM | 0.0351 mL | 0.1755 mL | 0.3511 mL | 0.8777 mL | |
| 60 mM | 0.0293 mL | 0.1463 mL | 0.2926 mL | 0.7314 mL | |
| 80 mM | 0.0219 mL | 0.1097 mL | 0.2194 mL | 0.5486 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
[D-Ala2]leucine-enkephalin Related Classifications
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